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KMID : 1007020090070020103
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Korean Soceity of Osteroporosis
2009 Volume.7 No. 2 p.103 ~ p.110
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Effects of Menopausal Symptoms, Hysterectomy and Bilateral Salpingoophorectomy on Bone Mineral Contents using Dual Energy X-Ray Absorptiometry
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Oh Young-Rim
Kim Heung-Yeol
Cha Hee-Jae
Ock Mee-Sun
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Abstract
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Objectives: Postmenopausal women suffer from hip fractures caused by osteoporosis that is primarily a consequence of the low estrogen levels of menopause. Bone density and the rate of bone loss may predicts the occurrence of osteoporosis-related symptoms in menopausal women. And surgically induced menopause is followed by a reduction of bone density throughout the body, so increase the risk of osteoporotic fractures. The purpose of this study was to examine the association between natural and surgically cally induced menopausal women with mean bone mineral densities.
Methods: After exclusion of women with spinal and other abnormalities, this study included 170 subjects: 75 who underwent natural menopause, 70 bilaterally salpingo-oophorectomized, and 25 hysterectomized without bilateral oophorectomy in the Department of Obstetrics and Gynecology at Kosin University Hospital from January 2008 to August 2008. Lumbar spine and femoral bone densities were measured by using dual energy X-ray absorptiometry (DEXA).
Results: The mean bone mineral densities of the surgically induced menopausal women were significantly lower than those of natural menopausal women (P<0.01). The mean bone mineral densities of the bilateral oophorectomized women were significantly lower than those of the natural menopausal, or hysterectomized women (P<0.01). A number of children and body weight were not significantly correlated with mean bone mineral densities. There were no significant differences in mean bone mineral densities between hormonal replacement therapy group and no hormonal replacement therapy group.
Conclusion: It is necessary that the surgically induced menopausal women should be checked up on the risk of osteoporosis and given the hormonal replacement therapy if mean bone mineral densities were below the critical level.
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KEYWORD
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Osteoporosis, Postmenopausal women, Mean bone mineral densities
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